Pelosi, a key player in the political shifts that eventually led to President Biden stepping down, has expressed deep sorrow over the strain in their relationship. Pelosi and Biden know each other for a long time, stretching back to when Joe Biden was an up-and-coming senator from Delaware and Pelosi was a committed Democratic volunteer and mother of five. Her San Francisco home served as a vital political gathering place, where Biden was a frequent guest, and Pelosi’s children even helped out during these influential events.